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Prurigo nodularis (PN) is a skin disease characterised by pruritic (itchy) nodules which usually appear on the arms or legs. Patients often present with multiple excoriated lesions caused by scratching. PN is also known as Hyde prurigo nodularis, ''Picker's nodules'', atypical nodular form of neurodermatitis circumscripta, lichen corneus obtusus. Lichen simplex chronicus is a distinct clinical entity. == Signs and symptoms == *Nodules are discrete, generally symmetric, hyperpigmented or purpuric, and firm. They are greater than 0.5 cm in both width and depth (as opposed to papules which are less than 0.5 cm). They can appear on any part of the body, but generally begin on the arms and legs. *Excoriated lesions are often flat, umbilicated, or have a crusted top. *Nodules may appear to begin in the hair follicles. *Nodule pattern may be follicular. *In true prurigo nodularis, a nodule forms before any itching begins. Typically, these nodules are extremely pruritic and are alleviated only by steroids. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Prurigo nodularis」の詳細全文を読む スポンサード リンク
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